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开心散源于《备急千金要方》,由人参、远志、茯苓和石菖蒲4味药组成,是中医益智安神的基本方剂之一。现代药理研究表明,开心散具有保护神经细胞、改善记忆、增强学习能力、抗抑郁和抗老年痴呆等作用。近年来,随着抑郁症和老年痴呆症患者数量的增加,开心散凭借其独特的优势,受到越来越多的关注,故该文对近年来关于开心散的文献进行了梳理,围绕开心散中的主要活性成分和开心散全方对于神经系统调控这一方面展开综述,以期为后续的研究提供参考。
Abstract:Kaixin San(开心散,KXS) originates from Thousand Golden Prescriptions,which is composed of Renshen(Ginseng Radix Et Rhizoma),Yuanzhi(Polygalae Radix),Fuling(Poria)and Shichangpu(Acori Tatarinowii Rhizoma). It is the basic prescription for tonifying and calming the mind in traditional Chinese medicine. Modern pharmacological studies have shown that KXS has the effects of protecting nerve cells,improving memory,enhancing learning ability,anti-depression and anti-Alzheimer's disease. In recent years,with the increase number of patients with depression and Alzheimer's disease,KXS has attracted more and more attention because of its unique advantages. Therefore,this article sorts out the references about KXS in recent years,focuses on the main active components and the whole prescription of KXS for regulating the nervous system,in order to provide reference for future research.
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基本信息:
DOI:10.13194/j.issn.1673-842x.2022.01.015
中图分类号:R285
引用信息:
[1]户京京,张晓光,杨建会,等.开心散神经系统作用现代研究[J].辽宁中医药大学学报,2022,24(01):61-66.DOI:10.13194/j.issn.1673-842x.2022.01.015.
基金信息:
国家“重大新药创制”科技重大专项(2018ZX09721-005)
2021-05-27
2021-05-27
2021-05-27