辽宁中医药大学学报

目的 探讨益气升降方联合坐式八段锦治疗左心衰竭患者临床疗效。方法 选择于医院就诊的左心衰竭患者112例，采取简单化分组方法分为两组各56例，对照组患者给予坐式八段锦治疗，观察组在对照组基础上给予益气升降方治疗，观察两组患者治疗前后临床疗效，中医证候积分，6 min步行试验，心功能指标（左室射血分数，左心室收缩末期内径，N末端B型钠尿肽前体），心肺运动指标（二氧化碳通气当量斜率，峰值摄氧量，最大通气量），神经内分泌激素水平（促肾上腺皮质激素，醛固酮，血管紧张素Ⅱ）及明尼苏达州心衰患者生活质量问卷评分。结果 治疗后观察组总有效率为91.67%显著高于对照组75%(P<0.05)；两组治疗后中医证候评分，左心室收缩末期内径、N末端B型钠尿肽前体、血清促肾上腺皮质激素、醛固酮、血管紧张素Ⅱ水平、二氧化碳通气当量斜率、明尼苏达州心衰患者生活质量问卷评分均较治疗前降低，且观察组低于对照组（P<0.05）；两组治疗后左室射血分数、峰值摄氧量、最大通气量、6 min步行距离均较治疗前升高，且观察组高于对照组（P<0.05）。结论 益气升降方联合坐式八段锦治疗左心衰竭患者临床疗效显著。

Objective To investigate the clinical efficacy of Yiqi Shengjiang Decoction（益气升降方） combined with seated Baduanjin in treating patients with left heart failure. Methods A total of 112 left heart failure patients admitted to our hospital were divided into two groups(56 cases each)using a simplified grouping method. The control group received seated Baduanjin therapy,while the observation group received Yiqi Shengjiang Decoction in addition to the control group's treatment. Clinical efficacy,traditional Chinese medicine syndrome scores,6-minute walk test,cardiac function indices(left ventricular ejection fraction,left ventricular end-systolic diameter,N-terminal pro-B-type natriuretic peptide),cardiopulmonary exercise indices(ventilatory equivalent for carbon dioxide slope,peak oxygen uptake,maximum ventilation volume),neuroendocrine hormone levels(adrenocorticotropic hormone,aldosterone,angiotensin Ⅱ),and Minnesota living with heart failure questionnaire scores were evaluated before and after treatment. Results After treatment,the total effective rate in the observation group was 91.67% significantly higher than that in the control group 75%(P<0.05). Post-treatment TCM syndrome scores,left ventricular end-systolic diameter,N-terminal pro-B-type natriuretic peptide,serum adrenocorticotropic hormone,aldosterone,angiotensinⅡ levels,ventilatory equivalent for carbon dioxide slope,and Minnesota living with heart failure questionnaire scores decreased in both groups compared to pre-treatment levels,with lower values in the observation group(P<0.05). Left ventricular ejection fraction,peak oxygen uptake,maximum ventilation volume,and 6-minute walk test distance increased in both groups post-treatment,with higher values in the observation group(P<0.05). Conclusion The combination of Yiqi Shengjiang Decoction and seated Baduanjin demonstrates significant clinical efficacy in treating patients with left heart failure.